Dissect cell-type differences, detect novel cell subtypes and biomarkers, define gene regulatory interactions, and decipher spatial gene expression patterns.
High-throughput single-cell and single-nucleus multi-omics platform for comprehensive molecular profiling.
The Chromium platform enables high-resolution omic analyses at the level of individual cells or nuclei, allowing detailed characterization of transcriptomes, genomes, and chromatin interactions on a per-cell basis.
It uses microfluidics based on “Gel Beads-in-Emulsion (GEMs)” technology to capture thousands of individual cells simultaneously.
Main applications:
Spatially resolved transcriptomic profiling to map gene expression within intact tissue architecture.
The Visium platform enables spatial gene expression analysis on tissue sections, preserving the positional context of transcripts within the native histological landscape.
Each spot on the capture area contains spatial barcodes that allow transcript mapping back to its original coordinates in the tissue, linking morphology and molecular identity.
Main applications:
High-resolution in situ transcriptomic imaging for single-cell and subcellular gene expression mapping.
The Xenium platform performs in situ RNA detection and quantification directly within preserved tissue sections, enabling precise localization of transcripts at single-cell and subcellular resolution.
It employs targeted fluorescent probes and high-resolution imaging to reveal cellular composition, spatial interactions, and tissue architecture.
Main applications: