CellSearch (Menarini Silicon Biosystems)
It allows the enrichment and enumeration of circulating tumor cells (CTCs) and circulating endothelial cells (CEC) from whole blood.
The CellSearch system is the first and the only FDA cleared blood test clinically validated for the detection and count of circulating tumor cells of epithelial origin (metastatic breast, prostate, and colorectal cancers). CellSearch system is pivotal in advancing research in various areas, particularly in cancer biology, metastasis, immunotherapy, and drug development, by enabling the isolation and analysis of CTCs for a deeper understanding of cancer and disease mechanisms.
The CellSearch system is widely used in cancer research for several purposes:
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Early detection and monitoring: it helps in studying circulating tumor cells (CTCs) for early cancer detection and monitoring treatment response.
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Immunotherapy and personalized medicine: researchers use it to track CTCs during immunotherapy and investigate personalized treatment strategies by analyzing genetic and molecular characteristics.
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Metastasis and drug resistance: it aids in understanding how CTCs contribute to metastasis and cancer progression, as well as how tumors develop resistance to therapies.